Dr Roy Lavendomme

@article{Xu2025,

title = {Engineering Cavity and Aperture Binding Sites Within a Metal–Organic Cage for Up‐ and Down‐Regulation of Catalysis},

author = {Yan Xu and Gen Li and Shihang Liang and Gaël De Leener and Michel Luhmer and Roy Lavendomme and En‐Qing Gao and Dawei Zhang},

doi = {10.1002/anie.202507981},

issn = {1521-3773},

year  = {2025},

date = {2025-09-15},

urldate = {2025-09-15},

journal = {Angew. Chem. Int. Ed.},

volume = {64},

number = {38},

pages = {e202507981},

publisher = {Wiley},

abstract = {Engineering molecular recognition events into catalytic systems to precisely control the up‐ or down‐regulation of catalysis in a biomimetic fashion is a challenging goal in supramolecular chemistry. In this work, we report on the construction of a new metal–organic cage, ZnII4L4 tetrahedron 1, using a protonated azacalix[3](2,6)pyridine‐based ligand as the capping faces. The cage features a large cavity and wide gaps between its faces, enabling the simultaneous binding of anionic guests centrally and peripherally. Encapsulation of α‐Mo8O264− within the T‐symmetric tetrahedron 1 leads to a C3‐symmetric inclusion complex Mo8O264−⊂1. The apertures of Mo8O264−⊂1 act as secondary binding sites for accommodating tetraarylborate guests or for providing access to the included Mo8O264− for catalyzing reactions. Catalytic experiments demonstrated that inclusion within 1 significantly enhances the catalytic activity of Mo8O264− for the oxidation of sulfides into sulfoxides. In contrast, peripheral binding of the bulky tetraarylborate anion to the inclusion complex Mo8O264−⊂1 effectively inhibits its catalytic activity by obstructing access to the catalytic active sites of Mo8O264−.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Carpentier2025c,

title = {Development of a water-soluble ouroboros-like calix[6]arene-trisimidazole-based ligand for enhanced binding of zinc},

author = {Romain Carpentier and Roy Lavendomme and Benoit Colasson and Kristin Bartik and Ivan Jabin},

doi = {10.1039/d4dt03158j},

issn = {1477-9234},

year  = {2025},

date = {2025-01-13},

journal = {Dalton Trans.},

volume = {54},

number = {3},

pages = {1052--1062},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {An ouroboros-like calix[6]arene-trisimidazole-based ligand was developed for the coordination of zinc in water.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2023c,

title = {Selective binding of oxalate by a tris-ureido calix[6]tube in a protic environment},

author = {Roy Lavendomme and Steven Moerkerke and Gaëlle Mariaule and Ivan Jabin},

doi = {10.1039/d3ob00947e},

issn = {1477-0539},

year  = {2023},

date = {2023-08-23},

journal = {Org. Biomol. Chem.},

volume = {21},

number = {33},

pages = {6730--6737},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {Tubular-shaped bis-calix[6]arenes possessing a small and rigid anion binding pocket are able to distinguish oxalate from other dicarboxylates.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2022c,

title = {Iteroselectivity, the missing sibling of chemo-, regio-, and stereoselectivities},

author = {Roy Lavendomme and Ivan Jabin},

doi = {10.1016/j.xcrp.2022.101121},

issn = {2666-3864},

year  = {2022},

date = {2022-11-00},

journal = {Cell Reports Physical Science},

volume = {3},

number = {11},

publisher = {Elsevier BV},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2019,

title = {Selective recognition of small hydrogen bond acceptors by a calix[6]arene-based molecular container},

author = {Roy Lavendomme and Florent Desroches and Steven Moerkerke and Filip Topić and Johan Wouters and Kari Rissanen and Michel Luhmer and Ivan Jabin},

doi = {10.1080/10610278.2019.1679374},

issn = {1029-0478},

year  = {2020},

date = {2020-01-02},

journal = {Supramolecular Chemistry},

volume = {32},

number = {1},

pages = {23--29},

publisher = {Informa UK Limited},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jabin2017,

title = {One-Step Synthesis of a Unique Molecular Platform for the Selective Functionalization of Calix[6]arenes},

author = {Ivan Jabin and Roy Lavendomme and Volodymyr Malytskyi and Jeremy Vandermeersch and Michel Luhmer},

doi = {10.1055/s-0036-1588681},

issn = {1437-210X},

year  = {2017},

date = {2017-02-15},

journal = {Synthesis},

volume = {49},

number = {05},

pages = {1009--1023},

publisher = {Georg Thieme Verlag KG},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2017,

title = {Encapsulation and solid state sequestration of gases by calix[6]arene-based molecular containers},

author = {Roy Lavendomme and Daniela Ajami and Steven Moerkerke and Johan Wouters and Kari Rissanen and Michel Luhmer and Ivan Jabin},

doi = {10.1039/c7cc03078a},

issn = {1364-548X},

year  = {2017},

date = {2017-00-00},

journal = {Chem. Commun.},

volume = {53},

number = {48},

pages = {6468--6471},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {
Calix[6]arene-based molecular containers can encapsulate small guests through a unique “rotating door” complexation process. The sequestration in the solid state of greenhouse gases is demonstrated.
},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2016,

title = {One Step Synthesis of Calix[\textit{n}]quin­ones through the HClO_{4}/PbO_{2}‐Mediated Oxidation of Calix[\textit{n}]arenes},

author = {Roy Lavendomme and Ludovic Troian‐Gautier and Sara Zahim and Olivia Reinaud and Ivan Jabin},

doi = {10.1002/ejoc.201600092},

issn = {1099-0690},

year  = {2016},

date = {2016-03-00},

journal = {Eur J Org Chem},

volume = {2016},

number = {9},

pages = {1665--1668},

publisher = {Wiley},

abstract = {AbstractA procedure using HClO4 and PbO2 allows the straightforward oxidation of para‐substituted and unsubstituted calix[n]arenes into the corresponding calix[n]quinones in approximately 82 % yield per quinone unit. These mild conditions constitute a good alternative to the classical procedure that involves highly toxic thallium(III) salts in trifluoroacetic acid.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2016b,

title = {A nano-sized container for specific encapsulation of isolated water molecules},

author = {Roy Lavendomme and Lionel Marcélis and Johan Wouters and Michel Luhmer and Ivan Jabin},

doi = {10.1039/c6cc08096k},

issn = {1364-548X},

year  = {2016},

date = {2016-00-00},

journal = {Chem. Commun.},

volume = {52},

number = {98},

pages = {14109--14112},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {
This calix[4]arene-based molecular box is able to encapsulate specifically two isolated water molecules in both non-protic and protic solvents.
},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zahim2016d,

title = {Triflate-functionalized calix[6]arenes as versatile building-blocks: application to the synthesis of an inherently chiral Zn(ii) complex},

author = {Sara Zahim and Roy Lavendomme and Olivia Reinaud and Michel Luhmer and Gwilherm Evano and Ivan Jabin},

doi = {10.1039/c5ob02367j},

issn = {1477-0539},

year  = {2016},

date = {2016-00-00},

journal = {Org. Biomol. Chem.},

volume = {14},

number = {6},

pages = {1950--1957},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {
The regioselective synthesis of two calix[6]arenes bearing triflate groups is described. These compounds constitute versatile molecular platforms that allow the elaboration of sophisticated calixarene-based systems selectively functionalized at the large and/or at the small rim.
},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2015b,

title = {Synthesis of (Homooxa)calixarene–Monoquinones through the “All-but-One” Methodology},

author = {Roy Lavendomme and Peter J. Cragg and Paula M. Marcos and Michel Luhmer and Ivan Jabin},

doi = {10.1021/acs.orglett.5b02985},

issn = {1523-7052},

year  = {2015},

date = {2015-11-20},

journal = {Org. Lett.},

volume = {17},

number = {22},

pages = {5690--5693},

publisher = {American Chemical Society (ACS)},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2015,

title = {Rational Strategies for the Selective Functionalization of Calixarenes},

author = {Roy Lavendomme and Sara Zahim and Gaël De Leener and Alex Inthasot and Alice Mattiuzzi and Michel Luhmer and Olivia Reinaud and Ivan Jabin},

doi = {10.1002/ajoc.201500178},

issn = {2193-5815},

year  = {2015},

date = {2015-08-00},

urldate = {2015-08-00},

journal = {Asian J. Org. Chem.},

volume = {4},

number = {8},

pages = {710--722},

publisher = {Wiley},

abstract = {Calixarenes are widely used as molecular platforms in supramolecular chemistry. Their efficient modification is key for appending functional moieties such as binding, sensing, chiral, or hydrophilic subunits. Due to the presence of multiple identical functional groups, selective functionalization of such macrocyclic compounds is highly challenging. Indeed, the control of the chemo‐, regio‐, stereo‐ as well as iteroselectivity is required. This review describes rational methods leading to a high degree of regio‐ and/or iteroselectivity and classifies them into specific strategies. Many of these strategies are conceptually very general and hopefully will be a source of inspiration for developing selective methods for other macrocyclic platforms.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lavendomme2014,

title = {Tailored Functionalization of Polyphenol-Based Molecular Platforms},

author = {Roy Lavendomme and Axel Leroy and Michel Luhmer and Ivan Jabin},

doi = {10.1021/jo501021c},

issn = {1520-6904},

year  = {2014},

date = {2014-07-18},

journal = {J. Org. Chem.},

volume = {79},

number = {14},

pages = {6563--6570},

publisher = {American Chemical Society (ACS)},

keywords = {},

pubstate = {published},

tppubtype = {article}

}